The Ratlas datasets
The Ratlas single-nucleus RNA-seq (snRNA-seq) datasets are currently composed of the following:
1) The rat nucleus accumbens (NAc), with samples taken from four experimental groups:
- Male adult rats, 1hr following saline injection
- Male adult rats, 1hr following cocaine injection (20mg/kg, I.P.),
- Female adult rats, 1hr following first saline injection
- Female adult rats, 1hr following first cocaine injection (20mg/kg, I.P.)
2) The rat nucleus accumbens (NAc), with samples taken from two experiments and eight experimental groups:
Acute - Rats received a single dose of saline or cocaine
- Male adult rats, 1hr following first saline injection
- Male adult rats, 1hr following first cocaine injection (20mg/kg, I.P.)
- Female adult rats, 1hr following first saline injection
- Female adult rats, 1hr following first cocaine injection (20mg/kg, I.P.)
Repeated - Rats received seven consecutive doses of saline or cocaine
- Male adult rats, 1hr following seventh saline injection
- Male adult rats, 1hr following seventh cocaine injection (20mg/kg, I.P.)
- Female adult rats, 1hr following seventh saline injection
- Female adult rats, 1hr following seventh cocaine injection (20mg/kg, I.P.)