The Ratlas datasets

The Ratlas single-nucleus RNA-seq (snRNA-seq) datasets are currently composed of the following:

1) The rat nucleus accumbens (NAc), with samples taken from four experimental groups:

  • Male adult rats, 1hr following saline injection
  • Male adult rats, 1hr following cocaine injection (20mg/kg, I.P.),
  • Female adult rats, 1hr following first saline injection
  • Female adult rats, 1hr following first cocaine injection (20mg/kg, I.P.)



2) The rat nucleus accumbens (NAc), with samples taken from two experiments and eight experimental groups:

     Acute - Rats received a single dose of saline or cocaine

  • Male adult rats, 1hr following first saline injection
  • Male adult rats, 1hr following first cocaine injection (20mg/kg, I.P.)
  • Female adult rats, 1hr following first saline injection
  • Female adult rats, 1hr following first cocaine injection (20mg/kg, I.P.)

     Repeated - Rats received seven consecutive doses of saline or cocaine

  • Male adult rats, 1hr following seventh saline injection
  • Male adult rats, 1hr following seventh cocaine injection (20mg/kg, I.P.)
  • Female adult rats, 1hr following seventh saline injection
  • Female adult rats, 1hr following seventh cocaine injection (20mg/kg, I.P.)